Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research
Date (from‐to) : 2017/04 -2020/03
Author : Kim Hunkyung
The prevalence of multiple frailty was 15.4%. Subjects with multiple frailty had significantly reduced MMSE score, grip strength, and usual walking speed; and higher GDS score, history of chronic disease such as heart disease, diabetes, osteoporosis, anemia, knee pain, urinary incontinence, and falls. Higher GDS score, not exercise habit, and having chronic diseases were significantly associated with multiple frailty, whereas greater MMSE score, knee extension strength, number of teeth, and usual walking speed had protective effects.
A total of 88 multiple frailty, elderly women over 65 years were randomly assigned to one of three groups: muscle strengthen exercise (M-Ex), cognitive stimulate exercise (C-Ex), and combined M-Ex and C-Ex group. The exercise group attended a 60-minute training program twice a week for three months. Significant group × time interactions were observed for grip strength (F-value= 5.589, P=0.006) and usual walking speed (F-value=9.343, P<0.001).